Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 7/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728385 | 0.90 | PIK3CD (0.35) | KDREPHB4ABL1EGFRHCK | |
| SCHEMBL31728351 | 0.90 | SRC (0.35) | KDREPHB4ABL1EGFRHCK | |
| SCHEMBL31728447 | 0.87 | EGFR (0.30) | KDREGFRERBB2 | |
| SCHEMBL31727822 | 0.86 | EIF2AK3 (0.31) | EIF2AK3 | |
| SCHEMBL31728959 | 0.84 | EPHB4 (0.36) | KDREPHB4ABL1EGFRHCK | |
| SCHEMBL31728925 | 0.81 | SRC (0.37) | KDRABL1EGFRSRC | |
| SCHEMBL31727749 | 0.81 | SRC (0.36) | KDREPHB4ABL1EGFRHCK | |
| SCHEMBL31727918 | 0.81 | — | — | |
| SCHEMBL31728961 | 0.79 | EGFR (0.38) | KDREPHB4ABL1EGFRHCK | |
| SCHEMBL31729157 | 0.78 | PDE5A (0.39) | KDREPHB4ABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |