Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | NSD2 | O96028 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | KAT7 | O95251 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728560 | 0.80 | JAK1 (0.35) | GPR119MAP4K4JAK1PDE10APDPK1 | |
| SCHEMBL31729167 | 0.77 | MAP4K4 (0.34) | MAP4K4 | |
| SCHEMBL31728431 | 0.77 | MAP4K4 (0.34) | MAP4K4 | |
| SCHEMBL31727883 | 0.68 | PDPK1 (0.35) | PDPK1 | |
| SCHEMBL31728059 | 0.66 | PDPK1 (0.37) | PDPK1 | |
| SCHEMBL31727794 | 0.66 | GRM5 (0.32) | NSD2 | |
| SCHEMBL17362697 | 0.64 | PDPK1 (0.39) | KAT7PDPK1 | |
| SCHEMBL17896412 | 0.64 | PDPK1 (0.45) | MAP4K4PDPK1 | |
| SCHEMBL30381388 | 0.63 | TRPA1 (0.40) | NSD2PDPK1 | |
| SCHEMBL17362870 | 0.61 | PDPK1 (0.40) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |