Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728073 | 0.80 | GPR119 (0.33) | JAK1MAP4K4PDE10AGPR119PDPK1 | |
| SCHEMBL31728059 | 0.77 | PDPK1 (0.37) | MKNK2PDPK1 | |
| SCHEMBL15274774 | 0.66 | GPR119 (0.38) | PDE10AGPR119 | |
| SCHEMBL19890726 | 0.63 | PDPK1 (0.35) | MKNK2PDPK1 | |
| SCHEMBL30167345 | 0.63 | PDPK1 (0.35) | MKNK2PDPK1 | |
| SCHEMBL20692747 | 0.63 | SRC (0.39) | PDPK1 | |
| SCHEMBL30813372 | 0.62 | LCK (0.35) | MKNK2PDPK1 | |
| SCHEMBL27455924 | 0.62 | LMNA (0.31) | — | |
| SCHEMBL21925311 | 0.62 | PDPK1 (0.43) | MAP4K4MKNK2PDPK1 | |
| SCHEMBL29921617 | 0.62 | PDPK1 (0.35) | MKNK2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |