Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853830 | 0.90 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3LMNA | |
| SCHEMBL6849821 | 0.88 | LMNA (0.40) | LMNAKMT2ASMN1; SMN2ALDH1A1ADORA2A | |
| SCHEMBL6855523 | 0.87 | TSHR (0.39) | NOTUMADRB3TMEM97HRH3TDP1 | |
| SCHEMBL24842047 | 0.87 | ADRB3 (0.40) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL31728124 | 0.86 | NOTUM (0.43) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL15199612 | 0.81 | ADRB3 (0.44) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL4784720 | 0.81 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3LMNA | |
| SCHEMBL6855922 | 0.80 | TBXAS1 (0.37) | NOTUMLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL23588215 | 0.79 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL21281675 | 0.79 | NOTUM (0.42) | NOTUMADRB3TMEM97HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |