Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728099 | 0.81 | HRH4 (0.32) | HRH4 | |
| SCHEMBL31728444 | 0.80 | OPRK1 (0.32) | HRH4KDM4EHTTOPRK1CHRNB2 | |
| SCHEMBL31727525 | 0.79 | HRH4 (0.34) | HRH4OPRK1ACACB | |
| SCHEMBL31728302 | 0.78 | F2RL1 (0.38) | HRH4F2RL1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL31728274 | 0.77 | CHRNB2 (0.37) | HRH4F2RL1HTTOPRK1CHRNB2 | |
| SCHEMBL30811846 | 0.77 | MAPT (0.37) | HRH4HTTCHRNB2CHRNA4MAPT | |
| SCHEMBL20354142 | 0.77 | ACACB (0.46) | HRH4OPRK1HTR3AACACB | |
| SCHEMBL31727694 | 0.76 | HRH4 (0.30) | HRH4 | |
| SCHEMBL20008586 | 0.76 | MAPK1 (0.39) | HTTOPRK1CHRNB2CHRNA4MAPT | |
| SCHEMBL31727780 | 0.75 | F2RL1 (0.36) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231561-A1 | TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |