SCHEMBL31728526

SCHEMBL31728526

CCn1nc(C)n(-c2ccc(Br)cc2)c1=O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 3/20 0.59
CYP2C19 P33261 2/20 0.54
POLB P06746 3/20 0.52
MAPT P10636 2/20 0.51
BCHE P06276 1/20 0.49
CHRNE Q04844 1/20 0.49
CYP2C9 P11712 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19643205 0.81 ROCK2 (0.63) CYP2C19POLBCYP2C9KMT2ANPSR1
SCHEMBL27267186 0.80 BRD9 (0.55) BRD9CYP2C19POLBMAPTBCHE
SCHEMBL11070469 0.78 BRD9 (0.54) BRD9CYP2C19POLBMAPTCYP2C9
SCHEMBL13114749 0.76 MAPT (0.40) BRD9CYP2C19POLBMAPTBCHE
SCHEMBL11075143 0.76 L3MBTL1 (0.65) BRD9CYP2C19POLBMAPTBCHE
SCHEMBL11069372 0.69 MAPT (0.49) BRD9CYP2C19POLBMAPTCYP2C9
SCHEMBL16196902 0.69 PPARD (0.48) MAPTLMNAALDH1A1NPC1RAB9A
SCHEMBL26756404 0.69 POLB (0.52) BRD9CYP2C19POLBKMT2ANPC1
SCHEMBL11072138 0.67 L3MBTL1 (0.61) BRD9CYP2C19POLBMAPTBCHE
SCHEMBL20639871 0.66 MAPT (0.49) MAPTLMNAALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025236004-A1 STAT6 INHIBITORS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed