Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.36 |
| ▸ | ADK | P55263 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | DHPS | P49366 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727967 | 0.94 | SRC (0.36) | SRCABL1EGFRKDRABL2 | |
| SCHEMBL31728927 | 0.90 | SRC (0.38) | SRCABL1EGFRKDRABL2 | |
| SCHEMBL31728959 | 0.85 | EPHB4 (0.36) | SRCABL1EGFRKDRMAP4K4 | |
| SCHEMBL31728886 | 0.81 | KDR (0.34) | SRCABL1EGFRKDR | |
| SCHEMBL31727782 | 0.80 | TLR7 (0.38) | SRCABL1EGFRKDR | |
| SCHEMBL31728393 | 0.78 | SRC (0.37) | SRCABL1EGFRKDRABL2 | |
| SCHEMBL31728374 | 0.77 | PIK3CD (0.32) | SRCABL1EGFRKDR | |
| SCHEMBL31727951 | 0.76 | DPP4 (0.33) | SRCABL1EGFRKDR | |
| SCHEMBL31728454 | 0.76 | EIF2AK3 (0.36) | EGFR | |
| SCHEMBL31729265 | 0.74 | MAP4K4 (0.43) | SRCABL1EGFRKDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |