Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | EIF2AK3 | Q9NZJ5 | 5/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728468 | 0.91 | ERBB2 (0.37) | EPHB4PIK3CDSRCPIK3CAPIK3CB | |
| SCHEMBL31727951 | 0.90 | DPP4 (0.33) | EPHB4PIK3CDSRCPIK3CAPIK3CB | |
| SCHEMBL31728454 | 0.89 | EIF2AK3 (0.36) | EPHB4EIF2AK3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31728235 | 0.89 | SCN9A (0.35) | EIF2AK3PTPN11DPP4 | |
| SCHEMBL31728925 | 0.85 | SRC (0.37) | SRCABL1EGFRKDRMAP4K4 | |
| SCHEMBL31728353 | 0.84 | HTR2C (0.36) | EPHB4EIF2AK3PIK3CDSRCPIK3CA | |
| SCHEMBL31727830 | 0.84 | HTR2C (0.36) | EPHB4EIF2AK3PIK3CDSRCPIK3CA | |
| SCHEMBL31728886 | 0.84 | KDR (0.34) | EPHB4EIF2AK3PIK3CDSRCPIK3CA | |
| SCHEMBL31728589 | 0.83 | SCN9A (0.32) | — | |
| SCHEMBL31727967 | 0.79 | SRC (0.36) | SRCABL1EGFRKDRMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |