Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358738 | 0.79 | ALOX15 (0.53) | RAB9ASMN1; SMN2ALOX15ADORA3ADORA2A | |
| SCHEMBL29941235 | 0.76 | TSHR (0.46) | TSHRKDM4EPOLBL3MBTL1 | |
| SCHEMBL11318893 | 0.75 | RAB9A (0.49) | TSHRRAB9ASMN1; SMN2ALOX15ADORA3 | |
| Methane SCHEMBL11192510 | 0.73 | TSHR (0.94) | TSHRKDM4EPOLBIDO1AGXT | |
| SCHEMBL26037955 | 0.71 | TSHR (0.52) | TSHRRAB9ASMN1; SMN2KDM4EIDO1 | |
| SCHEMBL27380 | 0.71 | TSHR (1.00) | TSHRKDM4EPOLBIDO1AGXT | |
| SCHEMBL5311581 | 0.71 | TSHR (1.00) | TSHRKDM4EPOLBIDO1AGXT | |
| Benzene SCHEMBL27997624 | 0.71 | TSHR (1.00) | TSHRKDM4EPOLBIDO1AGXT | |
| SCHEMBL7427308 | 0.70 | TSHR (0.50) | TSHRRAB9ASMN1; SMN2ALOX15CYP3A4 | |
| SCHEMBL9670868 | 0.69 | TSHR (0.75) | TSHRRAB9ASMN1; SMN2ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |