SCHEMBL31729068

SCHEMBL31729068

CCCCCCCCCCCCCCCCCCN1CCN(C)C1=N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
NPC1 O15118 11/20 0.39
RAB9A P51151 11/20 0.39
HTT P42858 9/20 0.39
LMNA P02545 7/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
NPSR1 Q6W5P4 6/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GALR3 O60755 3/20 0.39
POLB P06746 3/20 0.39
PAX8 Q06710 3/20 0.39
ATM Q13315 2/20 0.39
MAPK1 P28482 2/20 0.39
MAPT P10636 2/20 0.39
NR2F2 P24468 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31728966 1.00 GNAI3 (0.41) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL24420748 1.00 GNAI3 (0.41) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL11214414 0.87 MEN1 (0.44) GNAI3GNAO1GNAI1NPC1RAB9A
SCHEMBL16219094 0.83 MEN1 (0.32) RAB9AHTTMEN1KMT2AATM
SCHEMBL24052063 0.82 SIGMAR1 (0.32) LMNAMEN1KMT2A
SCHEMBL7593545 0.81 MEN1 (0.50) NPC1RAB9AHTTLMNASMN1; SMN2
SCHEMBL24052070 0.77 ALDH1A1 (0.36) LMNAMAPTKDM4EALDH1A1CYP2D6
SCHEMBL14344950 0.76
SCHEMBL10721244 0.76 GBA1 (0.44) GNAI3GNAO1GNAI1MAPTALDH1A1
SCHEMBL6561436 0.76 GBA1 (0.44) GNAI3GNAO1GNAI1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235911-A2 INHIBIN SUBUNIT BETA E-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2025-11-13 WO disclosed