Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.76 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.76 |
| ▸ | ATP4A | P20648 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | HRH2 | P25021 | 1/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | ATP4B | P51164 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208703 | 0.92 | ACHE (0.89) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11244717 | 0.89 | ACHE (0.84) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11244714 | 0.89 | ACHE (0.84) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11279602 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11211776 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11279600 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11208462 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11250179 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11250176 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11006146 | 0.88 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352506-A1 | MRGPRB2/X2, AGONIST AND ANTAGONIST AND METHODS THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250352506-A1 | MRGPRB2/X2, AGONIST AND ANTAGONIST AND METHODS THEREOF | MRGPRX2, MRGPRX1, MRGPRX4 | ACHE 1458/4885MEN1 3087/4885SLC22A1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.