Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.39 |
| ▸ | HPGD | P15428 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25733566 | 1.00 | KDM4E (0.42) | KDM4EHSD17B10GAAMAPK1GRIA1 | |
| SCHEMBL30254819 | 0.90 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL25737761 | 0.90 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL31731027 | 0.90 | ROCK2 (0.41) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL25733561 | 0.90 | ROCK2 (0.41) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL25275428 | 0.87 | HDAC1 (0.43) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL30439891 | 0.87 | HDAC1 (0.43) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL30902946 | 0.85 | PDE10A (0.40) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL25733565 | 0.85 | PDE10A (0.40) | KDM4EHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL25235923 | 0.85 | PIK3CA (0.38) | KDM4EHSD17B10GAAGRIA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | KDM4E 870/4885HSD17B10 4278/4885GAA 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.