Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731531 | 0.87 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL23541157 | 0.87 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL30274049 | 0.86 | DDB1 (0.62) | DDB1CRBN | |
| SCHEMBL25036212 | 0.86 | DDB1 (0.62) | DDB1CRBN | |
| SCHEMBL30289503 | 0.84 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL23541014 | 0.81 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL23540958 | 0.81 | CRBN (0.53) | DDB1CRBN | |
| SCHEMBL30258417 | 0.81 | CRBN (0.52) | DDB1CRBN | |
| SCHEMBL23541308 | 0.81 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL25034851 | 0.80 | DDB1 (0.60) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606533-B2 | 3-phenylpropylamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | SF1, SF3A1, SFXN1 | DDB1 1201/4885CRBN 2290/4885 |
| US-12606533-B2 | 3-phenylpropylamine derivative | SF3A1, SF1, HTR1D | DDB1 363/4885CRBN 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.