Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26266554 | 0.85 | CRBN (0.64) | CRBNDDB1ALOX5TNKS | |
| SCHEMBL31731890 | 0.85 | CRBN (0.64) | CRBNDDB1ALOX5TNKSKDM4E | |
| SCHEMBL31105686 | 0.85 | CRBN (0.64) | CRBNDDB1ALOX5TNKS | |
| SCHEMBL31158831 | 0.83 | CRBN (0.51) | CRBNDDB1ALOX5TNKSKDM4E | |
| SCHEMBL26502724 | 0.82 | CRBN (0.59) | CRBNDDB1ALOX5TNKSKDM4E | |
| SCHEMBL24777684 | 0.81 | CRBN (0.65) | CRBNDDB1ALOX5TNKSKDM4E | |
| SCHEMBL28511734 | 0.81 | ALOX5 (0.55) | CRBNDDB1ALOX5CFTRALDH1A1 | |
| SCHEMBL30830683 | 0.81 | CRBN (0.58) | CRBNDDB1 | |
| SCHEMBL29606370 | 0.80 | CRBN (0.69) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL23120492 | 0.80 | CRBN (0.69) | CRBNDDB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | UNIV DUNDEE (GB) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | PAICS, COASY, ABCG2 | CRBN 1827/4885DDB1 797/4885ALOX5 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.