SCHEMBL31733367

SCHEMBL31733367

COc1ccc([C@H](C)N)c(C2=CCN(C)CC2)c1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.55
DRD2 P14416 2/20 0.47
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
QDPR P09417 1/20 0.42
SIGMAR1 Q99720 2/20 0.41
DRD1 P21728 1/20 0.40
DRD5 P21918 1/20 0.40
DRD3 P35462 1/20 0.40
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31733726 1.00 SLC6A4 (0.55) SLC6A4DRD2ALDH1A1KMT2AQDPR
SCHEMBL5536929 0.77 SLC6A4 (0.61) SLC6A4DRD2ALDH1A1KMT2AQDPR
SCHEMBL31733788 0.76 SLC6A4 (0.47) SLC6A4DRD2ALDH1A1KMT2AQDPR
Hydrochloric Acid SCHEMBL31556090 0.74 QDPR (0.62) SLC6A4ALDH1A1KMT2AQDPRSIGMAR1
SCHEMBL28508682 0.74 SLC6A4 (0.57) SLC6A4DRD2ALDH1A1KMT2AQDPR
SCHEMBL5546728 0.73 QDPR (0.64) SLC6A4ALDH1A1KMT2AQDPRSIGMAR1
SCHEMBL7704740 0.71 SLC6A4 (1.00) SLC6A4DRD2
SCHEMBL5542027 0.70 QDPR (0.58) SLC6A4KMT2AQDPR
SCHEMBL24915928 0.69 SLC6A4 (0.46) SLC6A4DRD2QDPRHTR6
SCHEMBL7033282 0.68 QDPR (0.56) SLC6A4QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025237891-A1 QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2025-11-20 WO disclosed