Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915688 | 0.79 | MAPK14 (0.36) | — | |
| SCHEMBL24916054 | 0.74 | HTR1B (0.41) | HTR6 | |
| SCHEMBL24915974 | 0.70 | KMT2A (0.40) | — | |
| SCHEMBL29745140 | 0.69 | SLC6A4 (0.53) | SLC6A4DRD2HTR6FGFR3 | |
| SCHEMBL23122833 | 0.69 | SLC6A4 (0.53) | SLC6A4DRD2HTR6FGFR3 | |
| SCHEMBL24916052 | 0.69 | P2RX3 (0.37) | — | |
| SCHEMBL31733367 | 0.69 | SLC6A4 (0.55) | SLC6A4DRD2HTR6QDPR | |
| SCHEMBL31733726 | 0.69 | SLC6A4 (0.55) | SLC6A4DRD2HTR6QDPR | |
| SCHEMBL24916405 | 0.68 | HPGD (0.43) | — | |
| SCHEMBL5372625 | 0.67 | SLC6A4 (0.65) | SLC6A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | SLC6A4 4255/4885EHMT2 473/4885EHMT1 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.