Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 11/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 11/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 11/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31733591 | 0.80 | CA1 (0.38) | CA1CA2CA7CA9CA12 | |
| SCHEMBL31733731 | 0.79 | PDK1 (0.45) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10238670 | 0.73 | PDK1 (0.47) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4425315 | 0.71 | BRD4 (0.63) | CA1CA2CA7CA9CA12 | |
| SCHEMBL12476172 | 0.71 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13041657 | 0.71 | ALDH1A1 (0.51) | CA1CA2CA7CA9CA12 | |
| SCHEMBL19465749 | 0.71 | RORC (0.51) | CA1CA2CA7CA9CA12 | |
| SCHEMBL31733772 | 0.70 | CA12 (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL31733487 | 0.70 | CA12 (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2616853 | 0.69 | CA12 (0.44) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025237891-A1 | QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-11-20 | — | — | WO | disclosed |