Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536702 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL17329423 | 0.83 | ALDH1A1 (0.39) | ALDH1A1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL29717597 | 0.82 | GABRA1 (0.44) | ALDH1A1CYP2D6CYP1A2CYP3A4LMNA | |
| SCHEMBL50011 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4LMNAHIF1A | |
| SCHEMBL29364896 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4LMNAHIF1A | |
| SCHEMBL9960123 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNATSHR | |
| SCHEMBL6281523 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4LMNAHIF1A | |
| SCHEMBL56243 | 0.82 | GABRA1 (0.44) | ALDH1A1CYP2D6CYP1A2CYP3A4LMNA | |
| SCHEMBL16217127 | 0.82 | CYP1A2 (0.41) | ALDH1A1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL640982 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP2D6CYP1A2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025237891-A1 | QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-11-20 | — | — | WO | disclosed |