SCHEMBL31735367

SCHEMBL31735367

Cn1ncc(Nc2ccc3c(ccn3CCC3CCN(C(=O)OC(C)(C)C)CC3)c2)c(Cl)c1=O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 8/20 0.42
▸ GPR119 Q8TDV5 4/20 0.41
▸ BRD4 O60885 2/20 0.40
▸ KAT2B Q92831 1/20 0.40
▸ BRD9 Q9H8M2 1/20 0.40
▸ PIK3CA P42336 1/20 0.40
▸ PRKDC P78527 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735635 0.90 BPTF (0.46) BPTFBRD4KAT2BBRD9
SCHEMBL31735624 0.87 WEE1 (0.46) BPTFGPR119BRD4KAT2BBRD9
SCHEMBL31735869 0.83 PIK3CA (0.39) GPR119BRD4PIK3CAPRKDC
SCHEMBL31735742 0.83 BPTF (0.52) BPTFBRD4KAT2BBRD9
SCHEMBL31735875 0.80 BPTF (0.53) BPTFBRD4KAT2BBRD9
SCHEMBL31735699 0.79 PIK3CA (0.39) GPR119BRD4PIK3CAPRKDC
SCHEMBL31735881 0.78 BPTF (0.53) BPTFBRD4KAT2BBRD9
SCHEMBL31735640 0.77 BRD9 (0.41) BPTFBRD4KAT2BBRD9
SCHEMBL31735780 0.77 BPTF (0.51) BPTFBRD4KAT2BBRD9
SCHEMBL31735793 0.77 BPTF (0.51) BPTFBRD4KAT2BBRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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