SCHEMBL31735635

SCHEMBL31735635

CC(=O)N1CCC(CCn2ccc3cc(Nc4cnn(C)c(=O)c4Cl)ccc32)CC1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 13/20 0.46
▸ BRD4 O60885 4/20 0.43
▸ KAT2B Q92831 4/20 0.43
▸ BRD9 Q9H8M2 4/20 0.43
▸ KAT2A Q92830 1/20 0.42
▸ CECR2 Q9BXF3 1/20 0.42
▸ BRD7 Q9NPI1 1/20 0.42
▸ NR3C1 P04150 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735367 0.90 BPTF (0.42) BPTFBRD4KAT2BBRD9
SCHEMBL31735742 0.86 BPTF (0.52) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735875 0.83 BPTF (0.53) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735437 0.82 BPTF (0.46) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735743 0.82 NR3C1 (0.38) BPTFBRD4BRD9NR3C1
SCHEMBL31735881 0.82 BPTF (0.53) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735780 0.81 BPTF (0.51) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735640 0.81 BRD9 (0.41) BPTFBRD4KAT2BBRD9BRD7
SCHEMBL31735828 0.80 BPTF (0.61) BPTFBRD4KAT2BBRD9KAT2A
SCHEMBL31735675 0.79 BPTF (0.54) BPTFBRD4KAT2BBRD9KAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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