SCHEMBL31735699

SCHEMBL31735699

Cc1c(Nc2cc(Cl)cc3c2ccn3CCC2CCN(C(=O)OC(C)(C)C)CC2)cnn(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PIK3CA P42336 1/20 0.39
▸ PRKDC P78527 1/20 0.39
▸ GPR119 Q8TDV5 5/20 0.38
▸ BCDIN3D Q7Z5W3 1/20 0.38
▸ NPBWR1 P48145 1/20 0.38
▸ MCHR1 Q99705 1/20 0.38
▸ BRD4 O60885 1/20 0.38
▸ NR3C1 P04150 1/20 0.38
▸ MAPK8 P45983 3/20 0.37
▸ TP53 P04637 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ STS P08842 1/20 0.37
▸ DDB1 Q16531 1/20 0.37
▸ CRBN Q96SW2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735634 0.90 NR3C1 (0.38) BRD4NR3C1
SCHEMBL31735869 0.87 PIK3CA (0.39) PIK3CAPRKDCGPR119BCDIN3DNPBWR1
SCHEMBL31735427 0.83 BRD9 (0.42) BRD4
SCHEMBL31735367 0.79 BPTF (0.42) PIK3CAPRKDCGPR119BRD4
SCHEMBL31735812 0.78 STS (0.43) GPR119STS
SCHEMBL31735567 0.77 NR3C1 (0.38) BRD4NR3C1
SCHEMBL31735743 0.76 NR3C1 (0.38) BRD4NR3C1
SCHEMBL31735545 0.73 BRD4 (0.43) BRD4
SCHEMBL31735468 0.70 KDM4E (0.42) GPR119STS
SCHEMBL31735640 0.70 BRD9 (0.41) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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