SCHEMBL31735938

SCHEMBL31735938

COCCn1ccc2cc(Nc3cc(=O)n(C)c(=O)n3C)ccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ HAVCR2 Q8TDQ0 1/20 0.46
▸ GLO1 Q04760 2/20 0.44
▸ MAPT P10636 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ HDAC3 O15379 1/20 0.40
▸ HDAC1 Q13547 1/20 0.40
▸ HDAC2 Q92769 1/20 0.40
▸ HDAC8 Q9BY41 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ NCOR2 Q9Y618 1/20 0.40
▸ MTNR1A P48039 1/20 0.38
▸ MTNR1B P49286 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ HTR6 P50406 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ POLB P06746 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735377 0.80 GLO1 (0.47) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735659 0.76 GLO1 (0.44) MEN1KMT2AGLO1HDAC3HDAC1
SCHEMBL31735643 0.76 GLO1 (0.44) MEN1KMT2AGLO1HDAC3HDAC1
SCHEMBL31735820 0.75 GLO1 (0.42) MEN1KMT2AGLO1MAPTHDAC3
SCHEMBL13537466 0.75 GLO1 (0.47) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL28983113 0.74 GLO1 (0.45) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735420 0.73 GLO1 (0.41) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735846 0.73 GLO1 (0.40) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735425 0.72 BRD4 (0.41) GLO1HDAC3HDAC1HDAC2HDAC8
SCHEMBL31735661 0.72 GLO1 (0.40) MEN1KMT2AGLO1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
Send feedback