SCHEMBL31735518

SCHEMBL31735518

COCCn1ccc2cc(Nc3cnn(C4CCCCO4)c(=O)c3Cl)ccc21

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 9/20 0.38
▸ KAT2B Q92831 3/20 0.37
▸ RXRA P19793 1/20 0.35
▸ RXRB P28702 1/20 0.35
▸ RXRG P48443 1/20 0.35
▸ P2RX3 P56373 5/20 0.34
▸ BRD4 O60885 3/20 0.34
▸ BRD9 Q9H8M2 2/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ HTR6 P50406 1/20 0.34
▸ KAT2A Q92830 1/20 0.33
▸ CECR2 Q9BXF3 1/20 0.33
▸ BRD7 Q9NPI1 1/20 0.33
▸ GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735793 0.82 BPTF (0.51) BPTFKAT2BBRD4BRD9KAT2A
SCHEMBL31735470 0.81 BPTF (0.43) BPTFKAT2BP2RX3BRD4BRD9
SCHEMBL31735765 0.81 KAT2B (0.44) BPTFKAT2BBRD4BRD9HTR6
SCHEMBL31735442 0.80 BPTF (0.42) BPTFKAT2BP2RX3BRD4BRD9
SCHEMBL31735745 0.78 BPTF (0.41) BPTFKAT2BP2RX3BRD4BRD9
SCHEMBL31735397 0.77 RAB9A (0.40) BPTFKAT2BBRD4BRD9CNR2
SCHEMBL31735483 0.77 BPTF (0.45) BPTFKAT2BBRD4BRD9HTR6
SCHEMBL31735420 0.76 GLO1 (0.41) P2RX3CNR2HTR6GLO1
SCHEMBL31735856 0.75 BPTF (0.51) BPTFKAT2BBRD4BRD9KAT2A
SCHEMBL31735755 0.74 LMNA (0.40) P2RX3HTR6GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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