Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.45 |
| ▸ | CA9 | Q16790 | 11/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA6 | P23280 | 4/20 | 0.45 |
| ▸ | CA5A | P35218 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590932 | 1.00 | CA2 (0.45) | CA2CA9CA1CA12CA6 | |
| SCHEMBL32664646 | 0.84 | CA2 (0.42) | CA2CA9CA1CA12CA6 | |
| SCHEMBL21817054 | 0.78 | CA2 (0.42) | CA2CA9CA1CA12CA6 | |
| SCHEMBL16014743 | 0.75 | CA2 (0.39) | CA2CA9CA1CA12CA6 | |
| SCHEMBL6552316 | 0.73 | HTR2A (0.39) | — | |
| SCHEMBL8510502 | 0.72 | CA1 (0.47) | CA2CA9CA1CA12CA6 | |
| SCHEMBL202947 | 0.71 | CA2 (0.70) | CA2CA9CA1CA12CA6 | |
| SCHEMBL20153473 | 0.70 | PNMT (0.40) | CA2CA9CA1CA12CA6 | |
| SCHEMBL5500843 | 0.70 | CA2 (0.39) | CA2CA9CA1CA12CA6 | |
| SCHEMBL8193758 | 0.70 | SIGMAR1 (0.50) | CA2CA9CA1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245087-A1 | HETEROCYCLIC COMPOUNDS AS PARG INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |