Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15296459 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2ALMNAPOLBHSP90AA1 | |
| SCHEMBL4371076 | 0.85 | NPC1 (0.51) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL22989775 | 0.82 | GAA (0.46) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL15600324 | 0.80 | GAA (0.56) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL31738259 | 0.79 | GAA (0.51) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL22989973 | 0.75 | LMNA (0.49) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL22989810 | 0.75 | GAA (0.55) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL28774333 | 0.74 | RAB9A (0.47) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL31738321 | 0.74 | GAA (0.44) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL16774987 | 0.74 | GAA (0.52) | NPC1RAB9AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025243042-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILIN D | THE UNIVERSITY OF LIVERPOOL (GB) | 2025-11-27 | — | — | WO | disclosed |