Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857687 | 0.79 | MET (0.53) | JAK2METADRA2AADRA2BADRA2C | |
| SCHEMBL9125664 | 0.79 | MET (0.53) | JAK2METADRA2AADRA2BADRA2C | |
| SCHEMBL1921437 | 0.73 | MET (0.52) | METADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL15140610 | 0.73 | ALK (0.58) | JAK2METALK | |
| SCHEMBL2592205 | 0.73 | ALK (0.58) | JAK2METALK | |
| SCHEMBL15140533 | 0.72 | MET (0.60) | JAK2METALK | |
| SCHEMBL24006736 | 0.71 | JAK2 (0.54) | JAK2METALK | |
| SCHEMBL28380654 | 0.71 | JAK2 (0.69) | JAK2MET | |
| SCHEMBL24006750 | 0.71 | JAK2 (0.54) | JAK2METALK | |
| SCHEMBL15779022 | 0.71 | MET (0.62) | JAK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121045139-A | (R) -3- (1- ([ 1,1' -biphenyl ] -2-yl) ethoxy) pyridin-2-amine derivative and synthesis method and application thereof | 南方医科大学 | 2025-12-02 | — | — | CN | disclosed |
| CN-121045139-A | (R) -3- (1- ([ 1,1' -biphenyl ] -2-yl) ethoxy) pyridin-2-amine derivative and synthesis method and application thereof | 南方医科大学 | 2025-12-02 | — | — | CN | disclosed |