Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985198 | 0.87 | ALDH1A1 (0.49) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL18985201 | 0.83 | GAA (0.59) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL4458986 | 0.82 | GAA (0.54) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936614 | 0.81 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL19017268 | 0.81 | KMT2A (0.54) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL9937447 | 0.80 | ALDH1A1 (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9935825 | 0.79 | GAA (0.57) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936906 | 0.78 | GAA (0.51) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9935989 | 0.77 | GAA (0.59) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936025 | 0.77 | HTT (0.64) | GAAKDM4EMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, DHPS, MTAP | GAA 3858/4885KDM4E 1341/4885MAPT 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.