Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377756 | 0.81 | GPR88 (0.51) | GPR88 | |
| SCHEMBL15709788 | 0.81 | MAPK1 (0.50) | — | |
| SCHEMBL31395578 | 0.79 | MAPK1 (0.48) | GPR88 | |
| SCHEMBL31395596 | 0.79 | GPR88 (0.43) | GPR88 | |
| SCHEMBL30106066 | 0.77 | CYP11B1 (0.45) | — | |
| SCHEMBL15709873 | 0.75 | MAPT (0.42) | — | |
| SCHEMBL9314216 | 0.75 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL15709957 | 0.74 | MBOAT4 (0.42) | — | |
| SCHEMBL30106054 | 0.74 | MBOAT4 (0.42) | — | |
| SCHEMBL3210022 | 0.74 | NPC1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367158-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARM INC (US) | 2025-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367158-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR68, HTR2A | GPR88 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.