SCHEMBL3174196

SCHEMBL3174196

O=S(=O)(O)c1ccc(-c2ccncc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MAPT P10636 1/20 0.50
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
NT5E P21589 1/20 0.48
NAPRT Q6XQN6 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
CA2 P00918 4/20 0.46
CA1 P00915 2/20 0.46
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
QDPR P09417 1/20 0.43
NOTUM Q6P988 1/20 0.42
ENPP2 Q13822 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
PSEN1 P49768 1/20 0.42
PSEN2 P49810 1/20 0.42
APH1B Q8WW43 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7657523 0.87 MMP1 (0.44) LMNAMAPTTSHRALDH1A1NT5E
SCHEMBL28783303 0.85 TSHR (0.55) LMNAMAPTTSHRALDH1A1NT5E
SCHEMBL1416290 0.85 TSHR (0.55) LMNAMAPTTSHRALDH1A1NT5E
SCHEMBL447639 0.85 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL29990536 0.85 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL525918 0.85 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
SCHEMBL3171676 0.85 LMNA (0.65) LMNATSHRALDH1A1NT5ESMN1; SMN2
Pyridine SCHEMBL6115004 0.84 TSHR (0.56) LMNATSHRALDH1A1NT5ENAPRT
Hydrochloric Acid SCHEMBL27466287 0.83 TSHR (0.52) LMNAMAPTTSHRALDH1A1NT5E
Methane SCHEMBL28861733 0.83 TSHR (0.52) LMNAMAPTTSHRALDH1A1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP claimed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US claimed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP claimed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO claimed
EP-4398035-A1 WAFER EDGE PROTECTIVE-FILM-FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING Nissan Chemical Corporation (JP) 2024-07-10 EP disclosed
CN-118295212-A Composition for forming resist underlayer film containing glycol structure 日产化学株式会社 2024-07-05 CN disclosed
US-12025916-B2 Resist underlayer film-forming composition that contains triaryldiamine-containing novolac resin to which aromatic vinyl compound is added NISSAN CHEMICAL CORPORATION (JP) 2024-07-02 US disclosed
CN-118235092-A Polycyclic aromatic hydrocarbon-based photocurable resin composition 日产化学株式会社 2024-06-21 CN disclosed
US-20240168385-A1 PROTECTIVE FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2024-05-23 US disclosed
CN-117940849-A Wafer edge protection film forming composition for semiconductor manufacturing 日产化学株式会社 2024-04-26 CN disclosed
US-20230333474-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2023-10-19 US disclosed
US-20230317527-A1 WAFER TREATMENT METHOD NISSAN CHEMICAL CORPORATION (JP) 2023-10-05 US disclosed
CN-105849642-A Resist underlayer film forming composition containing copolymer having triazine ring and sulfur atom in main chain 日产化学工业株式会社 2016-08-10 CN disclosed
US-7651979-B2 SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-01-26 US disclosed
US-20050227290-A1 Novel coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-10-13 US disclosed
US-6806289-B1 SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-10-19 US disclosed
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP disclosed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US disclosed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP disclosed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO disclosed