SCHEMBL3174480

SCHEMBL3174480

Nc1ccccc1-c1c(N)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
HSD17B10 Q99714 4/20 0.60
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 3/20 0.42
GAA P10253 3/20 0.42
HPGD P15428 2/20 0.42
RAB9A P51151 2/20 0.42
ADORA3 P0DMS8 1/20 0.41
CYP3A4 P08684 2/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
IDO1 P14902 1/20 0.37
ADORA2A P29274 3/20 0.36
PTPRC P08575 1/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6579157 0.86 ALDH1A1 (0.67) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL5030574 0.83 HSD17B10 (0.48) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL1899394 0.81 HSD17B10 (0.46) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL675595 0.81 ALDH1A1 (0.50) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL573405 0.80 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDCYP3A4MAPT
SCHEMBL5146944 0.79 ALDH1A1 (0.63) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL2069055 0.78 HSD17B10 (0.48) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL25981 0.76 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL29407079 0.76 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL28465796 0.76 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116419581-A Ni-MOF frame-based Ni-MOF hole transport layer, perovskite solar cell and preparation method thereof 杭州纤纳光电科技有限公司 2023-07-11 CN claimed
CN-110649165-B Perovskite battery taking tetraphenyl biphenyl diamine derivative as hole transport material 中茂光伏科技集团有限公司 2024-06-04 CN disclosed
CN-110649165-B Perovskite battery taking tetraphenyl biphenyl diamine derivative as hole transport material 中茂光伏科技集团有限公司 2024-06-04 CN disclosed
CN-118119254-A Interface modification layer, perovskite solar cell and preparation method of perovskite solar cell 杭州纤纳光电科技有限公司 2024-05-31 CN disclosed
CN-117484917-A Mold capable of rapidly increasing and decreasing temperature for molding composite material and manufacturing method 上海晋飞碳纤科技股份有限公司 2024-02-02 CN disclosed
CN-116997223-A Lead halide recycling and utilizing method of perovskite solar cell 杭州纤纳光电科技有限公司 2023-11-03 CN disclosed
CN-116419581-A Ni-MOF frame-based Ni-MOF hole transport layer, perovskite solar cell and preparation method thereof 杭州纤纳光电科技有限公司 2023-07-11 CN disclosed
US-7652148-B1 Electrophilic aromatic substitution with diacyl imidazolium XEROX CORPORATION (US) 2010-01-26 US disclosed