SCHEMBL31744902

SCHEMBL31744902

Brc1ccc2[nH]cc(Oc3cccc4ccccc34)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
GPR84 Q9NQS5 1/20 0.43
NR4A2 P43354 1/20 0.40
HTR2A P28223 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
HTR1A P08908 2/20 0.39
CSNK2A1 P68400 1/20 0.38
SLC6A4 P31645 2/20 0.38
STING1 Q86WV6 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31744712 0.86 IDO1 (0.49) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744680 0.84 IDO1 (0.50) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744643 0.81 IDO1 (0.51) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744877 0.81 IDO1 (0.48) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744580 0.81 IDO1 (0.48) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744588 0.81 GPR84 (0.48) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31745806 0.80 CYP2A6 (0.44) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744596 0.79 IDO1 (0.48) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744822 0.79 RHEB (0.54) IDO1GPR84NR4A2HTR2ATRPM8
SCHEMBL31744563 0.78 GPR84 (0.46) IDO1GPR84NR4A2HTR2ATRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US claimed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 IDO1 38/4885GPR84 4183/4885NR4A2 1398/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 IDO1 38/4885GPR84 4183/4885NR4A2 1398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.