Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31745005 | 0.89 | ADORA1 (0.54) | ADORA1ADORA3ADORA2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL31745024 | 0.76 | ADORA2A (0.45) | ADORA1ADORA2A | |
| Trifluoroacetic Acid SCHEMBL6383554 | 0.70 | CYP2C19 (0.49) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL31745019 | 0.70 | ADORA2A (0.44) | ADORA1ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL31744975 | 0.69 | ADORA1 (0.47) | ADORA1ADORA3ADORA2AALDH1A1KMT2A | |
| Formic Acid SCHEMBL31744989 | 0.69 | ADORA2A (0.42) | ADORA1ADORA2AALDH1A1MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL31745124 | 0.69 | HDAC3 (0.39) | ADORA1ADORA2AHDAC3HDAC4HDAC1 | |
| SCHEMBL30647945 | 0.68 | ADORA3 (0.52) | ADORA1ADORA3HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL31570040 | 0.68 | KDM4C (0.47) | ADORA1ADORA2AHDAC3HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL31745043 | 0.67 | ADORA2A (0.44) | ADORA1ADORA2AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS INC (US) | 2025-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | ATXN2, SMN1; SMN2, ATXN10 | ADORA1 2438/4885ADORA3 519/4885ADORA2A 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.