Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744975 | 0.93 | ADORA1 (0.47) | ADORA2AADORA1TSHRHSD17B10CASP1 | |
| SCHEMBL31745005 | 0.72 | ADORA1 (0.54) | ADORA2AADORA1TSHRKMT2AALDH1A1 | |
| SCHEMBL31685021 | 0.70 | DCPS (0.46) | ADORA2ATSHRHSD17B10CASP1CASP7 | |
| Formic Acid SCHEMBL30763130 | 0.69 | ADORA2A (0.50) | ADORA2AADORA1NPC1RAB9APOLB | |
| Formic Acid SCHEMBL31745012 | 0.69 | ADORA2A (0.38) | ADORA2AADORA1TSHRHSD17B10NPC1 | |
| Trifluoroacetic Acid SCHEMBL31745076 | 0.69 | ADORA1 (0.46) | ADORA2AADORA1KMT2AALDH1A1PDE4A | |
| Formic Acid SCHEMBL6130009 | 0.68 | POLB (0.55) | ADORA2AADORA1TSHRHSD17B10NPC1 | |
| Formic Acid SCHEMBL31744976 | 0.67 | ADORA2A (0.36) | ADORA2AADORA1RAB9AKMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL31220481 | 0.66 | KDM4E (0.39) | TSHRHSD17B10CASP1CASP7NPC1 | |
| Formic Acid SCHEMBL30317221 | 0.65 | ALDH1A1 (0.34) | TSHRHSD17B10CASP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS INC (US) | 2025-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | ATXN2, SMN1; SMN2, ATXN10 | ADORA2A 1286/4885ADORA1 2438/4885TSHR 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.