Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16313909 | 1.00 | GPR52 (0.66) | GPR52 | |
| SCHEMBL3174683 | 1.00 | GPR52 (0.66) | GPR52 | |
| SCHEMBL9113431 | 0.89 | GPR52 (0.53) | GPR52 | |
| SCHEMBL10595578 | 0.87 | GPR52 (0.56) | GPR52 | |
| SCHEMBL10595585 | 0.87 | GPR52 (0.56) | GPR52 | |
| SCHEMBL2853636 | 0.84 | GPR52 (0.70) | GPR52 | |
| SCHEMBL2853640 | 0.84 | GPR52 (0.70) | GPR52 | |
| SCHEMBL2856224 | 0.84 | GPR52 (0.70) | GPR52 | |
| SCHEMBL6971328 | 0.82 | GPR52 (0.68) | GPR52 | |
| SCHEMBL9671273 | 0.81 | GPR52 (0.66) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963843-A | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2019-07-02 | — | — | CN | disclosed |
| WO-2018144869-A1 | COMPOSITONS AND METHODS FOR MODULATING UBA5 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-08-09 | — | — | WO | disclosed |
| US-20170166516-A1 | STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2017-06-15 | — | — | US | disclosed |
| EP-1660507-B2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | MILLENNIUM PHARM INC (US) | 2017-01-04 | — | — | EP | disclosed |
| WO-2016202808-A2 | NEW SYNTHESIS OF TAPENTADOL-HCl INTERMEDIATES | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2016-12-22 | — | — | WO | disclosed |
| EP-3105203-A1 | STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE | AZAD Pharmaceutical Ingredients AG (CH) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015121265-A1 | STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2015-08-20 | — | — | WO | disclosed |
| US-8075937-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | disclosed |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-12-17 | — | — | US | disclosed |
| US-7632531-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | International Flavors & Fragnances Inc. (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1473287-B1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INT FLAVORS & FRAGRANCES INC (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1473287-A2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040202619-A1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-10-14 | — | — | US | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-4948719-A | NONFOGGING, NONDELAMINATING | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040202619-A1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | TAS2R5, TAS2R4, TAS2R3 | GPR52 1550/4885 |
| US-20170166516-A1 | STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE | CYP2D6, CYP2C9, CYP3A43 | GPR52 1471/4885 |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | TAS2R5, TAS2R45, TAS2R16 | GPR52 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.