Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073922 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NLRP3LMNARXFP1RECQL | |
| SCHEMBL31162542 | 0.88 | NLRP3 (0.51) | ALDH1A1NLRP3LMNARXFP1RECQL | |
| SCHEMBL25073874 | 0.88 | NLRP3 (0.51) | ALDH1A1NLRP3LMNARXFP1RECQL | |
| SCHEMBL3038469 | 0.81 | MAPT (0.56) | ALDH1A1NLRP3LMNARECQLMAPT | |
| SCHEMBL31746969 | 0.78 | POLB (0.54) | NLRP3LMNARXFP1RECQLMAPT | |
| SCHEMBL25073867 | 0.78 | POLB (0.54) | NLRP3LMNARXFP1RECQLMAPT | |
| SCHEMBL25073775 | 0.78 | KDM4E (0.45) | ALDH1A1NLRP3LMNARXFP1MAPT | |
| SCHEMBL30279125 | 0.78 | KDM4E (0.45) | ALDH1A1NLRP3LMNARXFP1MAPT | |
| SCHEMBL25073828 | 0.77 | RXFP1 (0.47) | ALDH1A1NLRP3LMNARXFP1RECQL | |
| SCHEMBL25073923 | 0.76 | ELANE (0.53) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |