Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942741 | 0.92 | LCK (0.31) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3944854 | 0.92 | LCK (0.31) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3955143 | 0.92 | LCK (0.31) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL713873 | 0.80 | CHRM2 (0.35) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL2421695 | 0.79 | DNM1 (0.35) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31512361 | 0.77 | DNM1 (0.33) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3060071 | 0.73 | CHRM2 (0.39) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6977854 | 0.71 | DNM1 (0.42) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL19882685 | 0.71 | DNM1 (0.36) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL38651192 | 0.71 | DNM1 (0.43) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3003327-A1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | Tricida Inc. (US) | 2016-04-13 | — | — | EP | claimed |
| WO-2014197725-A1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | TRICIDA, INC. (US) | 2014-12-11 | — | — | WO | claimed |
| US-7645855-B2 | Condensation, solution polymerization of carbonates with diamines | BASF AKTIENGESELLSCHAFT (DE) | 2010-01-12 | — | — | US | claimed |
| US-20080306237-A1 | Highly Functional, Highly Branched Polyureas | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-11 | — | — | US | claimed |
| EP-1716197-B1 | HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS | BASF SE (DE) | 2008-10-29 | — | — | EP | claimed |
| EP-1685181-B1 | HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS | BASF SE (DE) | 2008-08-20 | — | — | EP | claimed |
| US-20070083030-A1 | Highly functional, highly branched polyureas | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-12 | — | — | US | claimed |
| EP-3003327-A1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | Tricida Inc. (US) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014197725-A1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | TRICIDA, INC. (US) | 2014-12-11 | — | — | WO | disclosed |