Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944854 | 1.00 | LCK (0.31) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3955143 | 1.00 | LCK (0.31) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3174692 | 0.92 | DNM1 (0.36) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14592914 | 0.75 | DNM1 (0.48) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL22808771 | 0.75 | LCK (0.44) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13855955 | 0.73 | DNM1 (0.52) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL713873 | 0.73 | CHRM2 (0.35) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL15130499 | 0.73 | LCK (0.43) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL2609751 | 0.73 | DNM1 (0.46) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13335703 | 0.73 | DNM1 (0.46) | LCKDNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049014-A2 | AMINE DENDRIMERS | Genzyme Corporation (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008011047-A2 | AMINE DENDRIMERS | GENZYME CORPORATION (US) | 2008-01-24 | — | — | WO | disclosed |