SCHEMBL31747479

SCHEMBL31747479

C#CCCCCc1ccc(C(=O)OC)cn1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ CYP4A11 Q02928 2/20 0.41
▸ CYP4F2 P78329 1/20 0.41
▸ MAOB P27338 4/20 0.41
▸ MAOA P21397 2/20 0.41
▸ MAPT P10636 4/20 0.39
▸ FAAH O00519 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ RAB9A P51151 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31747492 0.96 MAPK1 (0.49) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL22120004 0.87 MAPK1 (0.57) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL31747395 0.83 P4HA1 (0.43) L3MBTL1MAPTALDH1A1SMN1; SMN2
SCHEMBL845815 0.83 MAPK1 (0.53) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL31747404 0.83 CYP4A11 (0.60) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL13606287 0.83 CYP4A11 (0.60) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL20046826 0.82 CYP4A11 (0.59) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL31747416 0.82 CYP4A11 (0.59) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL13606302 0.82 CYP4A11 (0.59) MAPK1KDM4EL3MBTL1CYP4A11CYP4F2
SCHEMBL31747380 0.82 NNMT (0.44) KDM4EL3MBTL1FAAHSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
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