Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31747479 | 0.96 | MAPK1 (0.48) | MAPK1KDM4EL3MBTL1CYP4A11MAOB | |
| SCHEMBL22120004 | 0.85 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1CYP4A11MAPT | |
| SCHEMBL20503310 | 0.82 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1CYP4A11MAPT | |
| SCHEMBL31747413 | 0.82 | P4HA1 (0.44) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL13606287 | 0.81 | CYP4A11 (0.60) | MAPK1KDM4EL3MBTL1CYP4A11MAPT | |
| SCHEMBL845815 | 0.81 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1CYP4A11MAPT | |
| SCHEMBL31747404 | 0.81 | CYP4A11 (0.60) | MAPK1KDM4EL3MBTL1CYP4A11MAPT | |
| SCHEMBL31747260 | 0.81 | NNMT (0.45) | KDM4EL3MBTL1 | |
| SCHEMBL31752289 | 0.81 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1MAOBMAOA | |
| SCHEMBL31747416 | 0.80 | CYP4A11 (0.59) | MAPK1KDM4EL3MBTL1CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |