Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 4/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26096528 | 0.81 | CHUK (0.43) | CHUKLRRK2DYRK1ACCNT1CDK9 | |
| SCHEMBL24695937 | 0.75 | AXL (0.30) | — | |
| SCHEMBL29246467 | 0.75 | AXL (0.30) | — | |
| SCHEMBL21274452 | 0.71 | LRRK2 (0.53) | CHUKLRRK2DYRK1ACCNT1CDK9 | |
| SCHEMBL13834754 | 0.71 | LRRK2 (0.53) | CHUKLRRK2DYRK1ACCNT1CDK9 | |
| SCHEMBL8778840 | 0.71 | KHK (0.48) | CHUK | |
| SCHEMBL31748624 | 0.71 | CYP2A6 (0.41) | CCNT1CDK9HASPINIMPDH2 | |
| SCHEMBL16920114 | 0.70 | CSNK2A1 (0.60) | CHUKLRRK2DYRK1ASRCCCNT1 | |
| SCHEMBL30899087 | 0.70 | LRRK2 (0.47) | CHUKLRRK2DYRK1ACCNT1CDK9 | |
| SCHEMBL1564211 | 0.70 | LRRK2 (0.51) | CHUKLRRK2DYRK1ACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | BIOLEXIS THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | PRKAB2, PRKAB1, PRKAR2B | CHUK 538/4885LRRK2 145/4885DYRK1A 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.