Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751088 | 0.79 | RXRA (0.35) | DGAT2RETCNR1 | |
| SCHEMBL31750192 | 0.73 | — | — | |
| SCHEMBL31750165 | 0.71 | RXRA (0.37) | DGAT2RETCCNA2CDK2CCNA1 | |
| SCHEMBL31750162 | 0.71 | POLB (0.30) | — | |
| SCHEMBL31751081 | 0.70 | RXRA (0.36) | DGAT2CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL31750777 | 0.69 | RXRA (0.36) | DGAT2 | |
| SCHEMBL31750246 | 0.69 | SLC16A3 (0.33) | — | |
| SCHEMBL31750490 | 0.68 | RXRA (0.35) | DGAT2 | |
| SCHEMBL31750397 | 0.67 | GAA (0.33) | CDK2 | |
| SCHEMBL31750474 | 0.67 | HTR2C (0.30) | HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |