Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750246 | 0.82 | SLC16A3 (0.33) | — | |
| SCHEMBL31750137 | 0.82 | SCN9A (0.31) | — | |
| SCHEMBL31750192 | 0.81 | — | — | |
| SCHEMBL31750474 | 0.80 | HTR2C (0.30) | — | |
| SCHEMBL31750188 | 0.76 | P2RX7 (0.33) | — | |
| SCHEMBL31750397 | 0.72 | GAA (0.33) | — | |
| SCHEMBL31751095 | 0.71 | HTR2C (0.34) | — | |
| SCHEMBL31583192 | 0.67 | L3MBTL1 (0.38) | POLBMAPK1ATM | |
| SCHEMBL1259595 | 0.63 | HDAC6 (0.34) | — | |
| SCHEMBL31583219 | 0.58 | LMNA (0.35) | POLBMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |