Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171142 | 0.88 | HTR2A (0.47) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3161026 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL3177256 | 0.88 | GAA (0.49) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3161214 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3175213 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3161647 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3175029 | 0.84 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3175369 | 0.84 | GAA (0.47) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3176366 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAHTR2AL3MBTL1 | |
| SCHEMBL3171502 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |