Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161214 | 0.94 | ALDH1A1 (0.47) | GAAALDH1A1MAPTBCL9CTNNB1 | |
| SCHEMBL3161026 | 0.89 | ALDH1A1 (0.48) | GAAALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL3177256 | 0.87 | GAA (0.49) | GAAALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3182451 | 0.85 | ALDH1A1 (0.43) | GAAALDH1A1TDP1KMT2AMAPK1 | |
| SCHEMBL3168403 | 0.85 | L3MBTL1 (0.51) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL3175114 | 0.84 | ALDH1A1 (0.46) | GAAALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3161647 | 0.83 | ALDH1A1 (0.46) | GAAALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3171142 | 0.83 | HTR2A (0.47) | GAAALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3176366 | 0.83 | ALDH1A1 (0.49) | GAAALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL3175213 | 0.82 | ALDH1A1 (0.42) | GAAALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |