Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.47 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751895 | 0.89 | ADAM10 (0.48) | KDM4EABL1LMNAADAM10MMP1 | |
| SCHEMBL13015906 | 0.79 | KDM4E (0.64) | KDM4EABL1LMNAKMT2AHSD11B1 | |
| SCHEMBL29200952 | 0.76 | KDM4E (0.60) | KDM4EABL1LMNAKMT2AHSD11B1 | |
| SCHEMBL31751829 | 0.73 | SCN10A (0.45) | ADAM10MMP1MMP2MMP3MMP7 | |
| SCHEMBL31750971 | 0.73 | SCN10A (0.45) | ADAM10MMP1MMP2MMP3MMP7 | |
| SCHEMBL3773773 | 0.72 | KDM4E (0.62) | KDM4EABL1LMNAKMT2AHSD11B1 | |
| SCHEMBL31381191 | 0.70 | KDM4E (0.76) | KDM4EABL1LMNAKMT2AHSD11B1 | |
| SCHEMBL30540328 | 0.69 | LMNA (1.00) | KDM4EABL1LMNAKMT2AHSD11B1 | |
| SCHEMBL20458193 | 0.69 | CNR2 (0.62) | KDM4EABL1LMNAKMT2ACNR2 | |
| SCHEMBL4456801 | 0.68 | SMN1; SMN2 (0.51) | KDM4EABL1LMNAKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264645-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |