⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126446 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL31150 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL3400859 | 0.78 | — | — | |
| SCHEMBL21811862 | 0.77 | — | — | |
| SCHEMBL1049922 | 0.76 | ALOX15 (0.31) | — | |
| SCHEMBL28226113 | 0.76 | HCAR2 (0.41) | — | |
| Ethylene Glycol SCHEMBL7523660 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL11122611 | 0.73 | LMNA (0.32) | — | |
| Ethylene Glycol SCHEMBL7521890 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL2138366 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| CN-114585370-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585737-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114502177-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113748116-A | Techniques useful for oligonucleotide preparation | 波涛生命科学有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113444086-A | Ezh2 inhibitor and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113383078-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-107427521-B | Inhibitors of cyclin dependent kinases | 达纳-法伯癌症研究所股份有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-112218664-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112004928-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110698460-A | Heteroaryl compound, preparation method, pharmaceutical composition and application thereof | 隆泰申医药科技(南京) 有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-105849099-B | Polycyclic inhibitors of cyclin dependent kinase 7(CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-109136974-B | C (sp) -containing2) Process for producing (E) -N bond compound | 中国科学院上海有机化学研究所 | 2019-12-31 | — | — | CN | disclosed |
| CN-110582282-A | Triterpene saponin analogues | 佐剂技术公司 | 2019-12-17 | — | — | CN | disclosed |
| US-20100261908-A1 | PROCESSES FOR THE PREPARATION OF PRASUGREL , AND ITS SALTS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-14 | — | — | US | disclosed |
| EP-2205611-A2 | PROCESSES FOR THE PREPARATION OF PRASUGREL, AND ITS SALTS AND POLYMORPHS | Dr. Reddy's Laboratories Ltd. (IN) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009062044-A2 | PROCESSES FOR THE PREPARATION OF PRASUGREL, AND ITS SALTS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-05-14 | — | — | WO | disclosed |