Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17113076 | 0.80 | MEN1 (0.51) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL17544560 | 0.80 | KMT2A (0.51) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL4411556 | 0.79 | KMT2A (0.59) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1164954 | 0.77 | KMT2A (0.70) | MAPK1HSD17B10MEN1KMT2ARXFP1 | |
| SCHEMBL31753576 | 0.77 | KMT2A (0.70) | MAPK1HSD17B10MEN1KMT2ARXFP1 | |
| SCHEMBL1287113 | 0.77 | NPC1 (0.45) | MEN1KMT2AHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL4413578 | 0.76 | KMT2A (0.64) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL14597968 | 0.75 | HDAC1 (0.67) | MAPK1HSD17B10MEN1KMT2ARXFP1 | |
| SCHEMBL9736097 | 0.75 | KDM4C (0.54) | HSD17B10ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7654082 | 0.74 | MEN1 (0.56) | MAPK1HSD17B10MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025260159-A1 | ISOINDOLINE AND INDOLINE DERIVATIVE COMPOUNDS, COMBINATIONS, PHARMACEUTICAL COMPOSITIONS, MEDICAMENTS, USE OF THE COMPOUNDS AND METHOD OF TREATMENT OF PAIN | MICROBIOLÓGICA QUÍMICA E FARMACÊUTICA LTDA. (BR) | 2025-12-26 | — | — | WO | disclosed |