Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753620 | 0.83 | DCTPP1 (0.43) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30349708 | 0.79 | LMNA (0.43) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30588284 | 0.79 | LMNA (0.43) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11636961 | 0.79 | CYP1A2 (0.49) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL31752465 | 0.78 | HRH3 (0.54) | LMNAKMT2AKDM4EABL1GSK3B | |
| SCHEMBL11635317 | 0.77 | CYP1A2 (0.51) | HTTKDM4ECNR2 | |
| SCHEMBL31747419 | 0.77 | HRH3 (0.55) | LMNAKDM4EABL1 | |
| SCHEMBL5182925 | 0.76 | SCD (0.60) | MEN1KMT2ASMN1; SMN2SCDKDM4E | |
| SCHEMBL62904 | 0.75 | PARP1 (0.49) | HTTKDM4E | |
| SCHEMBL29942240 | 0.75 | BPTF (0.54) | HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |