Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171977 | 0.90 | ALDH1A1 (0.45) | SMN1; SMN2 | |
| SCHEMBL3175350 | 0.88 | LSS (0.39) | CHRM1ROCK2ROCK1HRH3ITGB3 | |
| SCHEMBL3156925 | 0.87 | MAPT (0.53) | SMN1; SMN2 | |
| SCHEMBL3163995 | 0.82 | KDM4E (0.50) | SMN1; SMN2 | |
| SCHEMBL3167885 | 0.81 | HTT (0.38) | — | |
| SCHEMBL3170303 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2 | |
| SCHEMBL3170897 | 0.79 | GRM5 (0.42) | SMN1; SMN2 | |
| SCHEMBL3171972 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2 | |
| SCHEMBL3157547 | 0.76 | CHRM3 (0.44) | HRH3 | |
| SCHEMBL3164002 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716128-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-BENZOTHIAZOL-2-YLAMINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2010-03-31 | — | — | EP | claimed |