Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169913 | 0.84 | CA2 (0.44) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL3169894 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL5945264 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL3179384 | 0.76 | — | — | |
| SCHEMBL16048554 | 0.73 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL19860980 | 0.73 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL27961887 | 0.71 | CA2 (0.46) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL8392143 | 0.70 | GABRA1 (0.54) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL138253 | 0.69 | CA2 (0.55) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL11568323 | 0.68 | ALDH1A1 (0.58) | CA2GABRA1GABRB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076430-B2 | Living radical polymerization promoter | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2133357-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | Otsuka Chemical Holdings Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | DNMT1, CYP1B1, DNMT3B | CA2 2689/4885GABRA1 3794/4885GABRB2 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.